Created by HANDMED

Created by HANDMED

 

 

 

 

Updated 24/08/2018

PUBLICATIONS //

2018

Gershkovitz M, Caspi Y, Fainsod-Levi T, Katz B, Michaeli J, Khawaled S, Lev S, Polyansky L, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Mori Y, Karni R, Fridlender ZG, Binshtok AM, Granot Z.(2018) TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells.Cancer Research 78(10):2680-2690.

2016

Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, Liu CM, Zhou M, Koh MJ, Chung H, Davidson SM, Luengo A, Wang AQ, Xu X, Yasgar A, Liu L, Rai G, Westover KD, Vander Heiden MG, Shen M, Gray NS, Boxer MB, Sabatini DM. (2016) A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nat Chem Biol . 6:452-8.

 

Shaul, YD **, Yuan, B., Thiru, P., Nutter-Upham, A., McCallum, S., Lanzkron, C., Bell, GW, Sabatini, DM **. (2016) MERAV: a tool for comparing gene expression across human tissues and cell types. Nucleic Acids Res. 44:560-6)..

2015

Patterson HC, Gerbeth C, Thiru P, Vögtle NF, Knoll M, Shahsafaei A, Samocha KE, Huang CX, Harden MM, Song R, Chen C, Kao J, Shi J, Salmon W, Shaul YD, Stokes MP, Silva JC, Bell GW, MacArthur DG, Ruland J, Meisinger C, Lodish HF. (2015) Respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. PNAS 112 (42): E5679-88.

2014

Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Prathapan T, Kim D, Kanarek N, Pacold ME, Possemato R, Chen WW, Bierie B, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM.  (2014) Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition. Cell 158:1094–1109.

 

Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y. (2014) Critical role of IL-1b in DNA damage-induce mucositis. PNAS 111 (6): E702-11.

2011

Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. (2011) Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 476 (7360): 346-50.

 

Lindquist RA, Ottina KA, Wheeler DB, Hsu PP, Thoreen CC, Guertin DA, Ali SM, Sengupta S, Shaul YD, Lamprecht MR, Madden KL, Papallo AR, Jones TR, Sabatini DM, Carpenter AE (2011) Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling. Genome Res 21 (3): 433-46.

2009

Shaul YD*, Gibor G*, Plotnikov A, Seger R. (2009) Specific phosphorylation and activation of ERK1c by MEK1b: A unique route in the ERK cascade. Gene & Dev 23 (15): 1779-90.

2008

Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM. (2008) The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 320 (5882): 1496-501

2007

Shaul YD, Seger R. (2007) The MEK/ERK cascade: specific signals to multiple functions. Biochim Biophys Acta. 1773 (8): 1213-26.

2006

Shaul YD, Seger R. (2006) The detection of MAPK signaling. Current Protocols in Molecular Biology. Chapter 18:Unit 18.12.

 

Shaul YD, Seger R. (2006) ERK1c regulates Golgi fragmentation during mitosis. J. Cell Biol. 172 (6): 885-97.

2005

Shaul, YD, Seger R. (2005) The detection of MAPK signaling. Current Protocols in Cell Biology. Chapter 14: Unit 14.3.

2004

Aebersold DM*, Shaul YD*, Yung Y*, Yarom N, Yao Z, Hanoch T, Seger R. (2004) ERK1c, a novel 42-kDa ERK demonstrates a unique mode of regulation, localization and function. Mol. Cell Biol. 24 (22): 10000-15.

 

Shaul YD, Seger R. (2004) The use of inhibitors in the study of MAPK signaling. Methods Mol Biol. (MAP Kinase Signaling Protocols. Seger, R. editor) 250: 113-26.

2002

Litvak V, Shaul YD, Shulewitz M, Amarilio R, Carmon S, Lev S. (2002) Targeting of Nir2 to lipid droplets is regulated by a specific threonine residue within its PI-transfer domain. Curr Biol. 12:1513-8

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